Cholecystectomy promotes the development of colorectal cancer by the alternation of bile acid metabolism and the gut microbiota
The incidence and mortality of colorectal cancer (CRC) have been markedly increasing worldwide, causing a tremendous burden to the healthcare system.Therefore, it is crucial to investigate the risk factors and pathogenesis of CRC.Cholecystectomy is a gold standard procedure for treating symptomatic cholelithiasis and gallstone diseases.The rhythm o